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  • 2 Mercaptoethanol and Peptide

2 Mercaptoethanol and Peptide

The relationship between dimercaptoethanol and peptides
Dimercaptoethanol is often related to peptides in the field of biochemistry. It is active and has significant effects in the research and synthesis of peptides.

Dimercaptoethanol has strong reduction ability, which is crucial for the structural maintenance and modification of peptides. There are often disulfide bonds between or within the chains of peptides, which have a great impact on the spatial structure and function of peptides. Dimercaptoethanol can break this disulfide bond, enable the structural development of peptides, and research assistants to explore the relationship between the fine structure and function of peptides.

And in the preparation process of peptides, dimercaptoethanol is also helpful. When synthesizing and purifying peptides, the structure is stable and will not be changed due to oxidation. If a peptide containing cysteine is prepared, dimercaptoethanol can protect its thiol group from endless oxidation into disulfide bonds, resulting in the loss of peptide activity.

Furthermore, dimercaptoethanol is also indispensable in the analysis and determination of peptides. When some analytical methods, such as electrophoresis, are used to measure the characteristics of peptides, dimercaptoethanol is added, which can make the peptide swim according to the expected state and help to obtain accurate analysis.

In summary, the relationship between dimercaptoethanol and peptides is very close. The research and application of peptides are all key elements that help the science of biochemistry to continue to advance.